In my research, I found no evidence or high-quality proof that the mRNA vaccine permanently alters or messes with immune systems. I did, however, discover that like any vaccine, the mRNA vaccine has the possibility of triggering an immune reaction while antibodies are being prepped and strengthened for future attacks to the system.
National Library of Medicine (Chen, 2023)
This article by the NLM gives a broad overview on the purpose and process of vaccines, specifically the mRNA vaccine. It explains that vaccines teach your body to fight against foreign attackers by introducing a small, rarely harmful, amount of genetic code to the immune system. The body then learns to recognize and break it down to create a stronger system, not destroy it.
Science (Goel, 2021)
This study specifically describes the long-lasting immune memory created after exposure to the mRNA vaccine. It explains that the temporary exposure often leads to future antibodies geared towards fighting off a real infection, which is opposite of "messing up" the immune system.
National Library of Medicine (Pardenas, 2025)
This article describes a study on the drop of antibodies in the following months after the mRNA vaccine. It finds that a drop is normal, and that your body won't be able to maintain high antibody levels forever but confirms that there are "memory cells" that will remember the attacking virus if exposed again.
In my research, I discovered the worries of altered immune systems following the mRNA vaccine is a normal reaction and a part of the antibody building process. To back up the statement, there is no need to worry about a future drop in antibodies because memory cells have a long-lasting ability to remember attacking viruses.