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in General Factchecking by Novice (610 points)
A growing number of people are reporting they have become pregnant after using GLP-1 drugs like Ozempic despite previous infertility or being on birth control pills.
by (140 points)
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This claim that Ozempic increases your chances of getting pregnant is not completely wrong, but is also not completely right. After reading an article by The Fertility Institute of San Diego, it has been found that Ozempic has helped women get to a better health state to become pregnant, but is not considered a fertility drug. Ozempic does help women with weight loss and the regulation of hormones which are two things that have been found to benefit the chances of pregnancy. I would consider this claim to be true as it may help other health factors that help increase pregnancy.

Source: https://fertilityinstitutesandiego.com/ozempic-and-increase-in-pregnancy-whats-the-fertility-connection/

35 Answers

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ago by Newbie (340 points)

This claim is partially correct but misleading at the same time. Ozempic can affect blood sugar and body weight which is linked to fertility. Which means technically it can get your body ready for pregnancy. However Ozempic is not considered safe for pregnant women to use and are not supposed to take it up to 2 months before becoming pregnant. Therefore Ozempic can make your put your body in a better state to become pregnant, however your not even supposed to be taking it under 2 months before pregnancy. 

"Since there's a close tie between blood sugar, body weight, and fertility, Ozempic seems like a possible tool to support women trying to become pregnant. The problem is that Ozempic is not considered safe for pregnant women and should be stopped when actively trying to conceive (TTC), so it's a delicate balance.

"Ozempic is not recommended for use during pregnancy, and those taking it are advised to stop at least two months before trying to become pregnant to make sure the medication is no longer in the body.  Since a significant number of pregnancies are unplanned, it’s usually recommended to use birth control while taking Ozempic."

https://www.signos.com/blog/ozempic-and-pregnancy

"In some studies examining small animals exposed to glucagon-like peptide-1 receptor agonists in pregnancy, there has been evidence of adverse outcomes in the offspring, including decreased fetal growth, skeletal and visceral anomalies, and embryonic death. "

"The safety box warning on the manufacturer of Semaglutide's website states, “It is not known if [Semaglutide] will harm your unborn baby or pass into your breast milk. You should stop using [Semaglutide] 2 months before you plan to become pregnant.”

https://www.sciencedirect.com/science/article/abs/pii/S0002937824008640

Exaggerated/ Misleading
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ago by Newbie (320 points)
GLP-1 drugs are not fertility treatments and will not solve infertility. They do, however, have a remarkable effect on fertility that has not yet been extensively researched, but seems promising.

One way in which drugs like Ozempic may improve fertility is by decreasing weight or BMI point. Research shows that for each BMI point above 29, female fertility is decreased by about 5%. By getting Ozempic users under this BMI, fertility is improved. GLP-1 drugs have also been shown to influence factors that are important when trying to get pregnant, including decreased inflammation, regulating testosterone levels, and encouraging ovulation. Drugs like Ozempic also impact the efficacy of birth control pills, as they slow down absorption. This means that birth control pills, which are absorbed similar to how the body absorbs food, will not be absorbed as well when using Ozempic.

https://health.clevelandclinic.org/ozempic-babies

Thus, while GLP-1 drugs are not fertility treatments, they do seem to lead to an increased chance of getting pregnant. However, more research should be done on whether they can be used as a fertility treatment and the magnitude of their effects on fertility.
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ago by Newbie (300 points)

A growing number of women are reporting unexpected pregnancies while using GLP-1 receptor agonist medications such as Ozempic (semaglutide), even among those who previously experienced infertility or were using oral contraceptives.This phenomenon, often referred to as "Ozempic babies," is attributed to two primary factors. First, GLP-1 drugs can slow gastric emptying, potentially reducing the absorption and effectiveness of oral contraceptives, especially during dosage adjustments . Second, these medications promote weight loss, which can restore ovulation and improve fertility in individuals with conditions like polycystic ovary syndrome (PCOS) . Medical experts advise that individuals using GLP-1 drugs who wish to avoid pregnancy should consider additional or alternative contraceptive methods, such as intrauterine devices (IUDs) or barrier methods . Furthermore, due to limited data on the safety of GLP-1 drugs during pregnancy and potential risks observed in animal studies, it is recommended to discontinue these medications at least two months prior to attempting conception

https://www.healthline.com/health-news/ozempic-babies-unplanned-pregnancies?utm_source

https://www.health.com/mounjaro-birth-control-side-effect-8374329?

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ago by Novice (900 points)

The claim that Ozempic increases chances of getting pregnant is at this point contentious, but scientific study seems to point toward the drug indirectly impacting users' fertility rates. According to Dr. Neha Lalani, who provides most of the oral account in the article linked above, GLP-1 (a semiglutide, the main active ingredient in Ozempic and other similar weight loss drugs according to the European Medicines Agency) increases the time it takes for the stomach to achieve an "empty" state, thus altering the way food and medications (including oral contraceptives) are absorbed into the body. Other publications, such as the Cleveland Clinic, seem to have come to similar conclusions. Again, while they don't necessarily know why GLP-1 agonists like Ozempic increase fertility rates in women, they do have theories, and they generally agree that there is some effect taking place. For one, the Cleveland Clinic study points out that "living with obesity — a body mass index (BMI) greater than 30 — can be a direct hit to your fertility." Therefore, any drug that lowers this statistic will inherently increase fertility, making it easier for those who may have struggled previously to become pregnant. That being said, hormonal birth controls that are not administered orally are seemingly unaffected by GLP-1 agonists; therefore, it is reasonable to conclude the drug has no direct effect on a person's fertility levels.

Healthline: https://www.healthline.com/health-news/ozempic-babies-unplanned-pregnancies#How-GLP-1-drugs-like-Ozempic-can-interfere-with-oral-birth-control

Cleveland Clinic: https://health.clevelandclinic.org/ozempic-babies

European Medicines Agency: https://www.ema.europa.eu/en/medicines/human/EPAR/ozempic#:~:text=The%20active%20substance%20in%20Ozempic,control%20of%20blood%20glucose%20levels.

Exaggerated/ Misleading
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ago by Novice (500 points)

The claim that Ozempic can increase chances of getting pregnant can be true when considering the side effects Ozempic has on the common body that can lead to fertility. For instance, Ozempic can cause someone to lose body fat from the hormonal imbalances, these imbalances then lead to fertility side effects while taking the drug. It’s not the drug itself that is causing this reaction but more the side effects that come from it. 

Ozempic and Pregnancy

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